Pharmacological Activity of Biosynthesized Gold Nanoparticles from Brown Algae- Seaweed Turbinaria conoides

Anuradha Venkatraman, Syed Ali Mohamed Yahoob, Yogananth Nagarajan, Sheeba Harikrishnan, Suganya Vasudevan and Tamizharasan Murugasamy
 

Abstract

The purpose of in vitro testing in the present study is to demonstrate the antidiabetic activity and anti-inflammatory activity of biosynthesized gold nanoparticle (AuNp) from Turbinaria conoides. The anti-diabetic activity by different in vitro methods method, anti-inflammatory activity by HRBC membrane stabilization assay and anticoagulant activity by calculating prothrombin time was carried out in the concentration range of (50 μl/ml, 100 μl/ml and 200 μl/ml) respectively. The inhibition rate of gold nanoparticle from Turbinaria conoides exhibited significantly maximum activity of 57.3% at concentration of 200 μg/ml and minimum level inhibition of 42.9% in 50 μl when compared with the standard drug Glinil that showed inhibition of maximum 85.6% and minimum 77.1%.

Published on: May 04, 2018
doi: 10.17756/nwj.2018-055
Citation: Venkatraman A, Yahoob SAM, Nagarajan Y, Harikrishnan S, Vasudevan S, et al. 2018. Pharmacological Activity of Biosynthesized Gold Nanoparticles from Brown Algae- Seaweed Turbinaria conoide. NanoWorld J 4(1): 17-22.

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